X-Ray Contrast Media : Overview, Use and Pharmaceutical Aspects.

Bibliographic Details
Main Author: Speck, Ulrich.
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin / Heidelberg, 2018.
Edition:5th ed.
Subjects:
Online Access:Click to View
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245 1 0 |a X-Ray Contrast Media :  |b Overview, Use and Pharmaceutical Aspects. 
250 |a 5th ed. 
264 1 |a Berlin, Heidelberg :  |b Springer Berlin / Heidelberg,  |c 2018. 
264 4 |c Ã2018. 
300 |a 1 online resource (128 pages) 
336 |a text  |b txt  |2 rdacontent 
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505 0 |a Intro -- CONTENT -- 1 INTRODUCTION -- Historical Aspects -- Contrast media in X-ray imaging -- Visualization of functions -- Morphology -- 2 GENERAL PRINCIPLES OF X-RAY CONTRAST MEDIA -- Physical Principles -- 3 STRUCTURE AND PROPERTIES OF X-RAY CONTRAST MEDIA -- Barium Sulfate -- Lipiodol -- Water-soluble contrast media -- Chemical structure, biological behavior and use -- High-osmolar, ionic contrast media -- Low-osmolar substances -- Nonionic contrast media -- Osmolality and side effects caused by hypertonicity -- Ionic contrast media -- Contrast media for intravenous cholegraphy -- Cations -- Synthesis of water-soluble contrast media -- 4 DEGRADATION OF IODINATED X-RAY CONTRAST MEDIA -- 5 PHYSICOCHEMICAL PROPERTIES OF WATER-SOLUBLE CONTRAST MEDIA -- Water solubility -- Viscosity/Temperature -- Osmolality -- Hydrophilia/Lipophilia -- Electrical charge -- Specific gravity/Density -- Others -- 6 PHARMACEUTICAL PRODUCT QUALITY -- Practical information at a glance -- Purity of the active ingredient, by-products and degradation products -- Formulations -- Additives -- Microbiological quality of the finished product -- Production under controlled environmental conditions -- Production process -- Sterile filtration, ultrafiltration and sterilization -- Sterility test -- Test for pyrogens -- Preservation of product quality in hospitals and practices -- Stability in long-term storage and at different temperatures -- Sensitivity to irradiation and light: white glass, brown glass, and UV-protective foil -- Tests for contamination with particles -- Risks of microbial contamination -- Transferring the contrast medium to sterile containers, disposable syringes, automatic injectors -- Transferring to sterile containers -- Drawing-up into disposable syringes or automatic injectors -- Use of large-volume CM bottles -- 7 PHARMACOLOGICAL PROPERTIES OF CM. 
505 8 |a Biochemical-pharmacological properties -- Protein binding -- Complement activation -- Enzyme inhibition -- Influence on blood cells -- Histamine release -- Pharmacological-Toxicological Properties -- Tolerance limits -- Effects on the cardiovascular system -- Influence on renal function -- Allergic and pseudoallergic hypersensitivity reactions -- Endothelial damage -- Nervous system -- Pharmacokinetics -- 8 USES OF X-RAY CONTRAST MEDIA -- Modes of opacification -- 9 INTERACTIONS -- Influence on laboratory tests -- Interaction with medications -- Interaction of contrast media with additives and during interventional procedures -- Effects on blood coagulation -- 10 RISKS OF CONTRAST MEDIA USE -- Barium sulfate -- Ionic contrast media -- Nonionic contrast media -- Delayed reactions -- Causes of contrast media reactions -- General reactions (anaphylactoid reactions) -- Prophylaxis of general reactions -- Dose-dependent side effects -- Prophylaxis and therapy of severe iodine-induced hyperthyroidism -- Renal damage -- Renal insufficiency -- Plasmocytoma -- Diabetes mellitus -- Prophylaxis -- Pregnant patients -- Breast-feeding mothers -- Pheochromocytoma -- Sickle-cell anemia -- 11 DRUGS AND MEASURES FOR THE TREATMENT OF A CONTRAST MEDIUM REACTION -- Notes on the prophylaxis and therapy of X-ray contrast medium adverse effects -- Main risk factors* and prophylactic measures on use of X-ray contrast media -- First line treatment of contrast medium adverse reactions -- 12 FURTHER DEVELOPMENT OF CONTRAST MEDIA -- REFERENCES. 
588 |a Description based on publisher supplied metadata and other sources. 
590 |a Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2023. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.  
655 4 |a Electronic books. 
776 0 8 |i Print version:  |a Speck, Ulrich  |t X-Ray Contrast Media  |d Berlin, Heidelberg : Springer Berlin / Heidelberg,c2018  |z 9783662564646 
797 2 |a ProQuest (Firm) 
856 4 0 |u https://ebookcentral.proquest.com/lib/matrademy/detail.action?docID=6422751  |z Click to View