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04950nam a22004333i 4500 |
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231204s2016 xx o ||||0 eng d |
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|a 9783319270692
|q (electronic bk.)
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|z 9783319270685
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|a (OCoLC)946516754
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|b eng
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|a QP34-38
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|a 612.022
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|a Sassone-Corsi, Paolo.
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| 245 |
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|a A Time for Metabolism and Hormones.
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|a 1st ed.
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| 264 |
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|a Cham :
|b Springer International Publishing AG,
|c 2016.
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| 264 |
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|c ©2016.
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| 300 |
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|a 1 online resource (141 pages)
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Research and Perspectives in Endocrine Interactions Series
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|a Intro -- Preface -- Acknowledgements -- Contents -- List of Contributors -- The Epigenetic and Metabolic Language of the Circadian Clock -- Introduction -- Chromatin Remodeling, Cyclic Transcription and the Clock -- Cellular Metabolism and the Circadian Clock Converge -- The Central Role of Sirtuins -- Conclusion -- References -- Molecular Architecture of the Circadian Clock in Mammals -- Introduction -- Structural Biology of Clock Proteins -- Transcriptional Architecture and Chromatin Dynamics of the Clock -- References -- Circadian Mechanisms in Bioenergetics and Cell Metabolism -- Genetic Approaches to Dissecting Circadian Physiology -- Clock-NAD+-Sirtuin Pathway in Bioenergetics -- Reciprocal Control of the Clock by Nutrient -- Summary and Future Directions -- References -- Control of Metabolism by Central and Peripheral Clocks in Drosophila -- Use of Drosophila to Study Behavior and Metabolic Function -- The Drosophila Fat Body Contains a Clock that Regulates a Rhythm of Feeding -- Fat Body and Neuronal Clocks Coordinately Regulate Metabolic Parameters -- Rhythmic Gene Expression in the Fat Body Is Controlled Largely, but not Exclusively, by the Fat Body Clock -- A Restricted Feeding Paradigm Resets the Phase of Cyclic Gene Expression in the Fat Body but not in the Brain -- Decoupling Peripheral and Brain Tissues Decreases Reproductive Fitness -- Metabolic Signals Also Affect Clocks in the Brain -- References -- Circadian Post-transcriptional Control of Metabolism -- Introduction -- Post-transcriptional Mechanisms -- Circadian Control of poly(A) Tail Length -- Nocturnin Is a Circadian Deadenylase -- Loss of Nocturnin Results in Broad Metabolic Changes -- Conclusions -- References -- Redox and Metabolic Oscillations in the Clockwork -- Introduction -- Challenging Transcriptional Models of the Clockwork -- Non-transcriptional Clock Mechanisms.
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|a PRDX Rhythms -- Redox and Metabolic Clocks in Eukaryotes -- Conclusion -- References -- Rev-erbs: Integrating Metabolism Around the Clock -- Introduction -- Repression of Transcription by Rev-erbs -- Circadian Biology of Rev-erbs -- Rev-erbα and Metabolism -- Conclusions -- References -- Control of Sleep-Wake Cycles in Drosophila -- Background -- Layout of the Network in Constant Conditions -- Network Architecture Under LD Cycles -- References -- Circadian Metabolomics: Insights for Biology and Medicine -- Introduction: A Many-Clock Problem -- An Overview of Circadian Metabolomics -- Metabolomics: Applications for Circadian Medicine -- Outlook and Conclusion -- References -- Rhythms Within Rhythms: The Importance of Oscillations for Glucocorticoid Hormones -- Introduction -- The Origin of HPA Pulsatility -- Implications of HPA Pulsatility -- Adrenal Adaptation to Pulsatile ACTH -- Tissue Adaptation to Pulsatile CORT -- Conclusion -- References -- The Genetics of Autism Spectrum Disorders -- Introduction -- Twin and Family Studies in ASD -- From Chromosomal Rearrangements to Copy Number Variants in ASD -- From Candidate Genes to Whole Exome/Genome Sequencing Studies in ASD -- The Common Variants in ASD -- The Genetic Architecture of ASD -- The Biological Pathways Associated with ASD -- The Serotonin-NAS-Melatonin Pathway -- Perspectives -- References -- Index.
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| 588 |
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|a Description based on publisher supplied metadata and other sources.
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| 590 |
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|a Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2023. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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| 655 |
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4 |
|a Electronic books.
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| 700 |
1 |
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|a Christen, Yves.
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| 776 |
0 |
8 |
|i Print version:
|a Sassone-Corsi, Paolo
|t A Time for Metabolism and Hormones
|d Cham : Springer International Publishing AG,c2016
|z 9783319270685
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| 797 |
2 |
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|a ProQuest (Firm)
|
| 830 |
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0 |
|a Research and Perspectives in Endocrine Interactions Series
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| 856 |
4 |
0 |
|u https://ebookcentral.proquest.com/lib/matrademy/detail.action?docID=5586353
|z Click to View
|
