Description: Economic Benefit of Tuberculosis Control

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Economic Benefit of Tuberculosis Control

Tuberculosis is the most important infectious cause of adult deaths after HIV/AIDS in low- and middle-income countries. This paper evaluates the economic benefits of extending the World Health Organization's DOTS Strategy (a multi-component ap...

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Bibliographic Details
Main Authors:	Laxminarayan, Ramanan, Klein, Eili, Dye, Christopher, Floyd, Katherine, Darley, Sarah, Adeyi, Olusoji
Language:	English
Published:	World Bank, Washington, DC 2012
Subjects:	ADULT MORTALITY AGED AGRICULTURAL DEVELOPMENT AGRICULTURAL PRODUCTION AIDS EPIDEMIC BASIC EDUCATION BLUEPRINT BURDEN OF DISEASE CAUSES OF DEATH CHEMOTHERAPY CHILD DEVELOPMENT CHRONIC DISEASE COMPLICATIONS COUNSELING CULTURAL CHANGE DEATH RATE DEATH RATES DEMOGRAPHIC TRANSITION DEVELOPING COUNTRIES DIAGNOSTICS DIET DISABILITY DISEASE DISEASE BURDEN DISEASE CONTROL DISEASE OF POVERTY DISEASE TRANSMISSION DRUG RESISTANCE DRUGS ECONOMIC GROWTH ECONOMIC PROSPERITY ENDEMIC COUNTRIES ENVIRONMENTAL PROTECTION EPIDEMIC EPIDEMICS EPIDEMIOLOGISTS EPIDEMIOLOGY EQUILIBRIUM EXISTING POPULATION EXPENDITURES FAMILIES FAMILY MEMBERS FERTILITY FORECASTS FUTURE GENERATIONS GLOBAL HEALTH HEALTH ECONOMICS HEALTH INTERVENTIONS HEALTH POLICY HEALTH SECTOR HEALTH SERVICES HEALTH STATUS HEALTH SYSTEMS HIV HIV TESTING HOUSEHOLD INCOME HUMAN CAPITAL HUMAN DEVELOPMENT HUMAN POPULATION ILLNESS IMMUNODEFICIENCY INFECTION INFECTIONS INFECTIOUS DISEASES INTERNATIONAL JOURNAL OF EPIDEMIOLOGY INTERVENTION INVESTMENT IN CHILDREN IRON JOURNAL OF MEDICINE LABOR MARKET LABOR SUPPLY LIFE EXPECTANCY LIVING CONDITIONS LIVING STANDARDS LONGER LIFE LONGEVITY LOW-INCOME COUNTRIES LOW-INCOME COUNTRY LUNG DISEASE M. BOVIS MALARIA MALNUTRITION MARKETING MEDICAL RESEARCH MEDICINE MIGRATION MILLENNIUM DEVELOPMENT GOALS MINISTRY OF HEALTH MORBIDITY MORBIDITY AND MORTALITY MORTALITY MORTALITY DECLINE MORTALITY DECLINES MORTALITY RATE MORTALITY REDUCTIONS MORTALITY RISK NUMBER OF DEATHS NUTRITION PACIFIC REGION PATIENTS POLICY RESEARCH POLICY RESEARCH WORKING PAPER POOR HEALTH PREMATURE DEATH PREVALENCE PROBABILITY PROGRESS PUBLIC HEALTH PUBLIC HEALTH PROGRAMS QUALITY OF HEALTH QUALITY OF LIFE REMITTANCES RESOURCE CONSTRAINTS RESPECT RISK FACTORS RISK OF DEATH RISK OF INFECTION RISK-TAKING BEHAVIOR RISKY BEHAVIOR SCHOOL CHILDREN SECONDARY SCHOOL SEX SOCIAL MOBILIZATION SUB-SAHARAN AFRICA SYNDROME TB TB CONTROL TOBACCO TRANSMISSION OF INFECTION TRANSMISSION RATES TREATMENT TUBERCULOSIS TUBERCULOSIS CONTROL UNEMPLOYMENT UNPROTECTED SEX VACCINE VACCINES WESTERN EUROPE WORKERS WORLD HEALTH ORGANIZATION YOUNG ADULTS
Online Access:	http://documents.worldbank.org/curated/en/2007/08/8011024/economic-benefit-tuberculosis-control http://hdl.handle.net/10986/7483

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Summary:	Tuberculosis is the most important infectious cause of adult deaths after HIV/AIDS in low- and middle-income countries. This paper evaluates the economic benefits of extending the World Health Organization's DOTS Strategy (a multi-component approach that includes directly observed treatment, short course chemotherapy and several other components) as proposed in the Global Plan to Stop TB, 2006-2015. The authors use a model-based approach that combines epidemiological projections of averted mortality and economic benefits measured using value of statistical life for the Sub-Saharan Africa region and the 22 high-burden, tuberculosis-endemic countries in the world. The analysis finds that the economic benefits between 2006 and 2015 of sustaining DOTS at current levels relative to having no DOTS coverage are significantly greater than the costs in the 22 high-burden, tuberculosis-endemic countries and the Africa region. The marginal benefits of implementing the Global Plan to Stop TB relative to a no-DOTS scenario exceed the marginal costs by a factor of 15 in the 22 high-burden endemic countries, a factor of 9 (95% CI, 8-9) in the Africa region, and a factor of 9 (95% CI, 9-10) in the nine high-burden African countries. Uncertainty analysis shows that benefit-cost ratios of the Global Plan strategy relative to sustained DOTS were unambiguously greater than one in all nine high-burden countries in Africa and in Afghanistan, Pakistan, and Russia. Although HIV curtails the effect of the tuberculosis programs by lowering the life expectancy of those receiving treatment, the benefits of the Global Plan are greatest in African countries with high levels of HIV.