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Prototype of a Biomimetic Multi-Spiked Connecting Scaffold for a New Generation of Resurfacing Endoprostheses.

This monograph explains prototype of the biomimetic Multi-Spiked Connecting Scaffold (MSC-Scaffold) fixing in the periarticular bone and the components of a new generation of entirely non-cemented resurfacing arthroplasty (RA) endoprostheses.

Bibliographic Details
Main Author: Uklejewski, Ryszard.
Other Authors: Rogala, Piotr., Winiecki, Mariusz.
Format: eBook
Language:English
Published: Milton : Taylor & Francis Group, 2023.
Edition:1st ed.
Subjects:
Electronic books.
Online Access:Click to View
Table of Contents:
  • Cover
  • Half Title
  • Title Page
  • Copyright Page
  • Dedication
  • Table of Contents
  • Forewords
  • Preface
  • Acknowledgements
  • About the Authors
  • Introduction
  • Chapter 1 Characteristics of Contemporary hip Resurfacing Arthroplasty Endoprostheses and their Possible Postoperative Complications
  • References
  • Chapter 2 Idea of Entirely Non-Cemented Implantation of the Components of hip Resurfacing Arthroplasty Endoprostheses with the Multi-Spiked Connecting Scaffold
  • References
  • Chapter 3 Design, Rapid Prototyping, and Manufacturing of the Biomimetic Multi-Spiked Connecting Scaffold Prototype for Non-Cemented Resurfacing Endoprostheses
  • 3.1 Bioengineering CAD Design and Modelling
  • 3.2 Methods and Effects of Electro-Erosion Machining
  • 3.3 Prototyping Spikes of the Multi-Spiked Connecting Scaffold by Stereolithography
  • 3.4 Prototyping and Manufacturing of the Multi-Spiked Connecting Scaffold and the total hip Resurfacing Endoprosthesis by Selective Laser Melting
  • 3.5 Post-production Treatment of the Bone-Contacting Surface of the Multi-Spiked Connecting Scaffold
  • 3.6 Reverse Design of the Working Prototype of Partial Resurfacing knee Arthroplasty Endoprosthesis
  • References
  • Chapter 4 Structural and Osteoconductive Functionalization of the Interspike Space of the Prototype Multi-Spiked Connecting Scaffold
  • 4.1 Assessment of the Pro-Osteoconductive Potential - Theoretical Basis
  • 4.2 Formation of the Structural and Osteoconductive Properties of the Multi-Spiked Connecting Scaffold
  • 4.3 Initial Evaluation in cell Culture of Structurally Functionalized Multi-Spiked Connecting Scaffold
  • 4.4 Pilot Study of Structurally Functionalized Multi-Spiked Connecting Scaffold in an Animal Model
  • References.
  • Chapter 5 Formation of Osteoinductive and Osseointegrative Properties of the Bone-Contacting Surface of the Multi-Spiked Connecting Scaffold Prototype by the Electrochemical Cathodic Deposition of Calcium Phosphates
  • 5.1 Initial Attempts to Modify the Surface of the Multi-Spiked Connecting Scaffold Preprototypes
  • 5.2 Research on the Process of Calcium Phosphate Potentiostatic Electrochemical Cathodic Deposition on the Surface of the Spikes with the Subsequent Immersion of the Preprototypes of the Multi-Spiked Connecting Scaffold in a Simulated body Fluid
  • 5.3 Evaluation in human Osteoblasts Culture of the Prototype Multi-Spiked Connecting Scaffold with Calcium Phosphate-Modified Bone-Contacting Surface
  • 5.4 Biointegration of the Prototype Multi-Spiked Connecting Scaffold with Calcium Phosphate Coating Implanted in Swine knee in Vivo
  • References
  • Chapter 6 Research on the System of bone and the Prototype Multi-Spiked Connecting Scaffold in order to Design the Structural and Biomechanical Properties of this System
  • 6.1 Numerical Study of the Influence of Geometric Features of the Multi-Spiked Connecting Scaffold on the Mechanical Stress Distribution in the Peri-Implant Bone
  • 6.2 Validation of the Numerical Model Reflecting the Embedment of the Prototype Multi-Spiked Connecting Scaffold in the Periarticular Bone
  • References
  • Chapter 7 Pilot Study on the Prototype Multi-Spiked Connecting Scaffold for Non-Cemented Resurfacing Endoprostheses in an Animal Model
  • 7.1 Experimental Determination of the Appropriate Surgical Approach to the hip and knee Joint in Swine
  • 7.2 Verification of the Working Prototype of Partial Resurfacing knee Arthroplasty Endoprosthesis in ten Experimental Animals
  • References.
  • Chapter 8 Pilot Micro-CT Study of the Impact of Embedding the Multi-Spiked Connecting Scaffold on the Density and Compressive Strength of the Subchondral Trabecular Bone of Femoral heads from Patients with Osteoarthritis
  • References
  • Chapter 9 Summary, Conclusions, and final Remarks
  • Conclusions and final Remarks
  • Appendixes
  • Appendix 1 - Patents front Pages Scans (US, Canada, Europe)
  • Appendix 2 - Letter of thanks from the Rector of the Poznan University of Technology, Poland
  • Index.

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