Micro-, Meso- and Macro-Connectomics of the Brain.
| Main Author: | |
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
Cham :
Springer International Publishing AG,
2016.
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| Edition: | 1st ed. |
| Series: | Research and Perspectives in Neurosciences Series
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| Subjects: | |
| Online Access: | Click to View |
Table of Contents:
- Intro
- Acknowledgments
- Contents
- List of Contributors
- Nanoconnectomics
- Nanoconnectomics
- Extracellular Space
- Simulating Signaling in Small Spaces
- Precision of Synaptic Plasticity
- References
- Inhibitory Cell Types, Circuits and Receptive Fields in Mouse Visual Cortex
- Differences in Connectivity, Visual Responses and Functional Impact of PV Versus SST Interneurons
- Calretinin (CR) and VIP-Expressing Interneurons Target SST Interneurons
- Functional Impact of VIP Interneurons
- References
- Form Meets Function in the Brain: Observing the Activity and Structure of Specific Neural Connections
- Introduction
- CLARITY
- Clarifying Large Tissue Volumes
- CLARITY-Optimized Light Sheet Microscopy
- Tracking Activity in Deep Genetically Targeted Neurons of Behaving Animals
- Neural Activity that Encodes and Predicts Social Interaction
- Outlook
- References
- The Network for Intracortical Communication in Mouse Visual Cortex
- Introduction
- Thalamocortical Projections to Mouse Visual Cortex
- Cortical Cartography
- Areal Organization of Visual Cortex
- Interareal Connections
- Cortical Hierarchy
- Synaptic Organization of Feedforward and Feedback Connections
- Dorsal and Ventral Processing Streams
- References
- The Brain in Space
- Introduction
- The Promise of Network Theory
- Empirical Evidence for a Principled Model of Cortical Connectivity: The EDR Model
- The Cortical Core-Periphery Structure
- Biology, Clustering and the Importance of Weak Links
- Conclusion and Perspectives
- References
- In-Vivo Connectivity in Monkeys
- Anatomical, Functional and Effective Connectivity in Animal Models
- Towards Causality: Effective Connectivity with Focal Perturbation Tools
- Effective Connectivity: Combined Electrical Microstimulation and Whole-Brain fMRI.
- Novel Genetically-Based Perturbation Methods?
- References
- Parcellations and Connectivity Patterns in Human and Macaque Cerebral Cortex
- Introduction
- Cortical Cartography and Parcellation
- Distributed Cortical Connectivity
- Interspecies Registration
- Concluding Comments
- References
- Connectome Networks: From Cells to Systems
- Defining the Connectome
- Brain Networks and Graph Theory
- Topology of Structural Brain Networks
- Microscale
- Mesoscale
- Macroscale
- Comparison Across Scales and Challenges
- Relations Between Structure and Function
- Microscale
- Mesoscale
- Macroscale
- Comparison Across Scales and Challenges
- Future Perspectives
- References
- Intra- and Inter-hemispheric Connectivity Supporting Hemispheric Specialization
- Introduction
- Human Dualism: Two Hands, Two Brains
- Asymmetries Measured with Brain Imaging
- Anatomo-Functional Support of HS
- Gray Matter Macroscopic Asymmetries and HS
- White Matter Connections Supporting HS
- Corpus Callosum
- Intra-hemispheric Structural Connectivity
- Functional Asymmetries and Hemispheric Dominance for Language Assessed with Meta-analysis
- Developmental Course of the Setting Up of Anatomical and Functional Asymmetries
- HS, Cognitive Abilities and Developmental/Psychiatric Diseases
- Cognitive Skills and Asymmetries
- Language HS, Developmental and Psychiatric Diseases
- Inter-individual Variability in HS: Factors at Play
- BILandGIN: A Multimodal Database for Investigating HS
- Conclusion
- References
- Genetics of the Connectome and the ENIGMA Project
- Background to ENIGMA
- Genetic Influences on the Brain
- Finding the Genes Involved
- GWAS of the Brain
- Counterarguments and Power
- Non-biological Information Arising from ENIGMA
- But Do the ENIGMA Genes Affect Disease Risk?
- Searching Brain Images for Statistical Effects.
- Brain-Wide Genome-Wide Scanning
- Genetic Screening of the Connectome
- Caveats for Multi-site Genomic Analysis of the Connectome
- Future Directions: Adaptive Connectomics and EPIC
- References
- Index.