On Protein Structure, Function and Modularity from an Evolutionary Perspective.
| Main Author: | |
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| Format: | eBook |
| Language: | English |
| Published: |
Linköping :
Linkopings Universitet,
2018.
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| Edition: | 1st ed. |
| Series: | Linköping Studies in Science and Technology. Dissertations Series
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| Subjects: | |
| Online Access: | Click to View |
Table of Contents:
- Intro
- Abstract
- Acknowledgments
- Author Contributions
- Contents
- List of Figures
- Abbreviations
- Introduction
- What is Science?
- Life and its Molecules
- Proteins - order and disorder
- Systems
- Thesis
- Method
- Alignments
- Contact prediction
- Structure prediction
- Dynamics simulation
- Clustering analysis
- Essential Dynamics Analysis
- Graphs and Structures
- Allosteric Network Analysis
- Ensemble Quality Assessment
- Present Investigations
- Function in transiently ordered islets of intrinsically disordered proteins (Paper I)
- Functional analysis of protein structure dynamics using graph models and multivariate statistics (Paper II)
- Improvements in Protein Model Quality Assessment from Automated Domain Partitioning using Spectral Clustering (Paper III and Manuscript I)
- Functional Interaction Network of c-MYC Conserved Regions determined by Evolutionary Couplings (Manuscript II)
- Conclusion
- Future Perspectives
- Bibliography
- Paper I
- Paper II
- Paper III
- Manuscript I
- Manuscript II.