Interactions Between the Brain and the Immune System in Pain and Inflammation. - Zajdel, Joanna (Linköping : Linkopings Universitet, 2019)
Paper II: Calcitonin gene related peptide is dispensable for many danger-related motivational responses -- CGRP is absent in the projections to the central amygdala in CGRP-KO mice -- CGRP signaling is not necessary for inflammation induced anorexia and conditioned taste aversion -- CGRP signaling is not necessary for pain-related behaviors -- Paper III: Acute maternal separation potentiates the gene expression and corticosterone response induced by inflammation -- Maternal separation slightly attenuates proinflammatory gene induction one hour after inflammatory challenge without affecting CORT levels -- Maternal separation potentiates proinflammatory gene induction and CORT response three hours after inflammatory challenge -- A warm and soft object attenuates some of the effects of separation stress -- Corticosterone levels correlate with IL-6, Ccl2 and hepatic IL-1 expression -- Conclusions -- Paper I: Prostaglandin-mediated inhibition of serotonin signaling controls the affective component of inflammatory pain -- Paper II: Calcitonin gene related peptide is dispensable for many danger-related motivational responses -- Paper III: Acute maternal separation potentiates the gene expression and corticosterone response induced by inflammation -- Bibliography.
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Keywords: Electronic books