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Evaluation of the Dual-Modal Usage of Contrast Agents by Means of Synchrotron X-Ray Computed Microtomography and Magnetic Resonance Imaging Using Macrophages Loaded with Barium Sulfate and Gadolinium Nanoparticles for Detection and Monitoring in Animal Di.

Bibliographic Details
Main Author: Larsson, Emanuel.
Format: eBook
Language:English
Published: Linköping : Linkopings Universitet, 2015.
Edition:1st ed.
Series:Linköping Studies in Science and Technology. Dissertations Series
Subjects:
Electronic books.
Online Access:Click to View
Table of Contents:
  • Intro
  • Dedication
  • Abstract
  • Populärvetenskaplig sammanfattning
  • Sommario
  • List of publications
  • Author's Contribution
  • Related publications
  • Contents
  • List of Figures
  • Acronyms
  • 1 Introduction
  • 1.1 Objective
  • 1.2 Thesis outline
  • 2 Contrast Agents
  • 2.1 Contrast agents for Computed Tomography
  • 2.2 Contrast agents for Magnetic Resonance Imaging
  • 2.3 Selection and development of a multi-modal contrast agent for MRI and CT
  • 3 Animal Disease Models
  • 3.1 Experimental design
  • 3.1.1 Pilot studies &amp
  • sample sizes
  • 3.2 Selection of an animal disease model expressing inflammations
  • 3.2.1 Animal model used in this thesis - an asthmatic mouse model
  • 4 Tomographic Imaging Modalities
  • 4.1 Computed Tomography
  • 4.1.1 Production of Conventional X-rays
  • 4.1.2 Experimental setup of CT vs -CT
  • 4.1.3 Synchrotron Radiation-CT
  • 4.1.4 Synchrotron Radiation-CT vs conventional -CT
  • 4.1.5 X-rays interaction with matter and the attenuation of X-rays
  • 4.1.6 Image quality
  • 4.2 Magnetic Resonance Imaging
  • 4.2.1 NMR Background
  • 4.2.2 Net magnetization
  • 4.2.3 Relaxation
  • 4.2.4 Image contrast
  • 4.2.5 Encoding the MR-signal
  • 4.2.6 Imaging parameters
  • 5 Image Post Processing
  • 5.1 Image Quality
  • 5.2 Segmentation Techniques
  • 5.3 Volume Rendering
  • 5.4 Selection of Volume of Interest
  • 5.5 Quantitative &amp
  • Statistical Image Analysis
  • 5.6 Image Registration
  • 6 Summary of papers
  • 6.1 Paper I:
  • 6.2 Paper II:
  • 6.3 Paper III:
  • 6.4 Paper IV:
  • 6.5 Paper V:
  • 7 Final discussion
  • 8 Future Outlook
  • Acknowledgments
  • Bibliography.

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